Dr. Chen earned his PhD from The University of Chicago, and performed postdoctoral studies at MIT and the Broad Institute. His research focuses on global understanding of biological systems. He has led studies on identifying and characterizing genes of new origin in eukaryotic genomes, essential function of new genes in animal development and tumorigenesis, microRNA regulation of hypoxia and angiogenesis, in vivo modeling of lung cancer and liver cancer using gene editing, and genome-wide in vivo screens. His research team is interested in developing and applying novel tools for next generation cancer genetics, genomics and systems biology, and tackle problems in cancer initiation, progression, metastasis, immunity, and therapeutic responses.

Website: https://medicine.yale.edu/genetics/people/sidi_chen.profile