Dr. Alan Wong's research topics focus on developing and applying cutting-edge technologies for studying complex disease biology and devise new therapeutic strategies. Many human diseases are caused by multigenic perturbations. His research takes an integrative approach leveraging on various techniques in synthetic biology, CRISPR-based genome engineering, high-throughput sequencing, molecular biology, and genetics to decode the complex genetic bases of human diseases including cancers and neurodegenerative disorders. His laboratory aims to develop and apply new technologies to interrogate and understand the complex biological systems, and rationally design and engineer genetic circuits for providing new biomedical and biotechnological solutions. Website: http://www.sbms.hku.hk/research/aslw/index.html