Matthew Lorincz received his Doctor of Philosophy from the Stanford University School of Medicine. Lorincz leads research focused on the interplay between transcription, DNA methylation, and histone modifications during early development, using mice as a model system. His lab employs CRISPR/Cas9 and genetic knockouts, alongside genome-wide analyses, to explore the roles of specific epigenetic marks in gene regulation. Ongoing projects include investigating the interactions of histone modifications H3K36me2 and H3K27me3 in embryonic development, examines the heritability of histone modifications and DNA methylation through fertilisation in hybrid mice; and studies the roles of H3K9 methyltransferases in transcription regulation and the impact of LTR-initiated transcripts on imprinting in oocytes. Lorincz has published extensively in leading journals, including Nature Genetics, Science, and Developmental Cell, contributing significantly to the understanding of how epigenetic mechanisms influence gene expression and genome stability in development and health.