Registration

Opening ceremony: welcome address

Kathryn Cheah, Course Director, Advanced Study Institutes
Michael Hausser, Director, School of Biomedical Sciences, HKUMed

Open lecture 1: Reconstructing development at single cell resolution

Session chairs: Pengtao Liu and Yuanhua Huang

Gene context drift - a new approach to discover treatment targets in rare and common cancers
Richard Gilbertson

Discussion

Tea break

Open lecture 2: Single cell multiomics technology development

Session chairs: Pak Sham and Tom Cheung

Single-cell multi-omics: technologies, applications, and computational inference
Xi Chen
Yuanhua Huang

Discussion

Lunch and welcome mixer for ASI lecturers and registrants

[Closed Session for accepted ASI registrants only]

Workshop 1: Integrating multiomics data: Challenges, practical considerations and solutions in single cell research

[Closed Session for accepted ASI registrants only]
Session chair: David Shih

Gene context drift - a new approach to study biological states over time
Richard Gilbertson (with assistance from Amir Jassim) 

Tea break

[Closed Session for accepted ASI registrants only]

Workshop 2: Integrating and interpreting multiomics data

[Closed Session for accepted ASI registrants only]
Session chair: David Shih

Hands-on analysis of single-cell and spatial omics data
Xi Chen
Yuanhua Huang (with the assistance from Mingze Gao)

Open lectures 3: Gene regulation in development and disease

Session chairs: Kathryn Cheah and Pengtao Liu

Human development and evolution through the gene regulatory lens
Joanna Wysocka

Discussion

Tea break

Workshop 3: Decoding regulatory complexity

[Closed Session for accepted ASI registrants only]
Session chair: Yuanhua Huang 

Computational analysis of epigenomic data 
Joanna Wysocka (with assistance from Tomasz Swigut)

Lunch

[Closed Session for accepted ASI registrants only]

Open lecture 4: Stem cells, organoids and disease models

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[UPDATED - To be conducted via Zoom]
Zoom Link: https://hku.zoom.us/j/92967166573?pwd=6T9Lo9PEwfXaOo8Z70FP4LkXpYjG0g.1 
Meeting ID: 929 6716 6573
Password: 633457
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Session chair: Andras Nagy and Pengtao Liu

Precision medicine redefined: organoids and the future of tailored chronic lung disease therapies
Shafagh Waters

Discussion

Tea break

Open lecture 5: Multi-scale imaging of living cells and organisms

------------------------------
[UPDATED - To be conducted via Zoom]
Zoom Link: https://hku.zoom.us/j/92967166573?pwd=6T9Lo9PEwfXaOo8Z70FP4LkXpYjG0g.1 
Meeting ID: 929 6716 6573
Password: 633457
------------------------------
Session chairs: Zhiqin Chu and David Shih

Live-cell super-resolution microscopy from general applicability to quantitative evaluation: a personal journey for the last ten year
Liangyi Chen

Discussion

Lunch

[Closed Session for accepted ASI registrants only]

Workshop 4: Recent advances in organoid technologies: Applications and challenges

[Closed Session for accepted ASI registrants only]
Session chairs: Andras Nagy and Mu He

Adult stem cells and mucosal organoids: revolutionising airway and gut disease models for precision care
Shafagh Waters

Tea break

[Closed Session for accepted ASI registrants only]

Workshop 5: Advanced super-resolution image computation and processing

[Closed Session for accepted ASI registrants only]
[Hands-on training to be conducted in CPOS]
Session chair: Zhiqin Chu 

Sparse deconvolution: detailed protocol and steps
Liangyi Chen (with the assistance from Bo Zhou)

Open lecture 6: Multi-scale imaging of living cells and organisms

Session chairs: Tom Cheung & Kenneth Wong

3D imaging of live multicellular specimens and cleared tissues using tiling light sheet microscopy
Liang Gao

Discussion

Tea break

Selected talk by registrant I

[Closed Session for accepted ASI registrants only]
Session chair: David Shih

CIVA - Modelling spatial neighborhoods that determine CAR-T efficiency by Cancer-Immune-Vascular Assembloids
Rio Sugimura 

Discussion

Selected talk by registrant II

[Closed Session for accepted ASI registrants only]
Session chair: David Shih

Integrating single-cell RNA-seq and spatial transcriptomics reveals the role of MMP14 as an immune-related regulator for endochondral bone integrity
Anna Xiaodan Yu

Discussion

Selected talk by registrant III

[Closed Session for accepted ASI registrants only]
Session chair: David Shih

High-throughput, in-depth, label-free, imaging flow cytometry
Kelvin Chak Man Lee

Discussion

Lunch

[Closed Session for accepted ASI registrants only]

Workshop 6: Decoding large neural networks with advanced light sheet microscopy

[Closed Session for accepted ASI registrants only]
Session chairs: Zhiqin Chu and Mu He

Imaging large neural networks using tissue clearing, tissue expansion and tiling light sheet microscopy techniques
Liang Gao (with the assistance from Jiongfang Xie)

Tea break

[Closed Session for accepted ASI registrants only]

Discussion session on hot topics

[Closed Session for accepted ASI registrants only]
Session chair: Tom Cheung

Engineering and harnessing safe and immune-invisible cells to deliver therapeutic biologics
Andras Nagy

Closing remarks

Kathryn Cheah, Course Director, Advanced Study Institutes