Programme
Programme
Day 1
09:00 — 09:30
Registration
09:30 — 09:45
Opening ceremony: welcome address
Kathryn Cheah, Course Director, Advanced Study Institutes
Michael Hausser, Director, School of Biomedical Sciences, HKUMed
09:45 — 11:15
Open lecture 1: Reconstructing development at single cell resolution
Session chairs: Pengtao Liu and Yuanhua Huang
Gene context drift - a new approach to discover treatment targets in rare and common cancers
Richard Gilbertson
Discussion
11:15 — 11:30
Tea break
11:30 — 13:00
Open lecture 2: Single cell multiomics technology development
Session chairs: Pak Sham and Tom Cheung
Single-cell multi-omics: technologies, applications, and computational inference
Xi Chen
Yuanhua Huang
Discussion
13:00 — 14:30
Lunch and welcome mixer for ASI lecturers and registrants
[Closed Session for accepted ASI registrants only]
14:30 — 16:00
Workshop 1: Integrating multiomics data: Challenges, practical considerations and solutions in single cell research
[Closed Session for accepted ASI registrants only]
Session chair: David Shih
Gene context drift - a new approach to study biological states over time
Richard Gilbertson (with assistance from Amir Jassim)
16:00 — 16:15
Tea break
[Closed Session for accepted ASI registrants only]
16:15 — 17:45
Workshop 2: Integrating and interpreting multiomics data
[Closed Session for accepted ASI registrants only]
Session chair: David Shih
Hands-on analysis of single-cell and spatial omics data
Xi Chen
Yuanhua Huang (with the assistance from Mingze Gao)
Day 2
09:30 — 11:00
Open lectures 3: Gene regulation in development and disease
Session chairs: Kathryn Cheah and Pengtao Liu
Human development and evolution through the gene regulatory lens
Joanna Wysocka
Discussion
11:00 — 11:15
Tea break
11:15 — 12:45
Workshop 3: Decoding regulatory complexity
[Closed Session for accepted ASI registrants only]
Session chair: Yuanhua Huang
Computational analysis of epigenomic data
Joanna Wysocka (with assistance from Tomasz Swigut)
12:45 — 14:15
Lunch
[Closed Session for accepted ASI registrants only]
Day 3
09:30 — 11:00
Open lecture 4: Stem cells, organoids and disease models
-----------------------------
[UPDATED - To be conducted via Zoom]
Zoom Link: https://hku.zoom.us/j/92967166573?pwd=6T9Lo9PEwfXaOo8Z70FP4LkXpYjG0g.1
Meeting ID: 929 6716 6573
Password: 633457
------------------------------
Session chair: Andras Nagy and Pengtao Liu
Precision medicine redefined: organoids and the future of tailored chronic lung disease therapies
Shafagh Waters
Discussion
11:00 — 11:15
Tea break
11:15 — 12:45
Open lecture 5: Multi-scale imaging of living cells and organisms
------------------------------
[UPDATED - To be conducted via Zoom]
Zoom Link: https://hku.zoom.us/j/92967166573?pwd=6T9Lo9PEwfXaOo8Z70FP4LkXpYjG0g.1
Meeting ID: 929 6716 6573
Password: 633457
------------------------------
Session chairs: Zhiqin Chu and David Shih
Live-cell super-resolution microscopy from general applicability to quantitative evaluation: a personal journey for the last ten year
Liangyi Chen
Discussion
12:45 — 14:00
Lunch
[Closed Session for accepted ASI registrants only]
14:00 — 15:30
Workshop 4: Recent advances in organoid technologies: Applications and challenges
[Closed Session for accepted ASI registrants only]
Session chairs: Andras Nagy and Mu He
Adult stem cells and mucosal organoids: revolutionising airway and gut disease models for precision care
Shafagh Waters
15:30 — 15:45
Tea break
[Closed Session for accepted ASI registrants only]
15:45 — 17:15
Workshop 5: Advanced super-resolution image computation and processing
[Closed Session for accepted ASI registrants only]
[Hands-on training to be conducted in CPOS]
Session chair: Zhiqin Chu
Sparse deconvolution: detailed protocol and steps
Liangyi Chen (with the assistance from Bo Zhou)
Day 4
09:30 — 11:00
Open lecture 6: Multi-scale imaging of living cells and organisms
Session chairs: Tom Cheung & Kenneth Wong
3D imaging of live multicellular specimens and cleared tissues using tiling light sheet microscopy
Liang Gao
Discussion
11:00 — 11:15
Tea break
11:15 — 11:40
Selected talk by registrant I
[Closed Session for accepted ASI registrants only]
Session chair: David Shih
CIVA - Modelling spatial neighborhoods that determine CAR-T efficiency by Cancer-Immune-Vascular Assembloids
Rio Sugimura
Discussion
11:40 — 12:05
Selected talk by registrant II
[Closed Session for accepted ASI registrants only]
Session chair: David Shih
Integrating single-cell RNA-seq and spatial transcriptomics reveals the role of MMP14 as an immune-related regulator for endochondral bone integrity
Anna Xiaodan Yu
Discussion
12:05 — 12:30
Selected talk by registrant III
[Closed Session for accepted ASI registrants only]
Session chair: David Shih
High-throughput, in-depth, label-free, imaging flow cytometry
Kelvin Chak Man Lee
Discussion
12:30 — 14:00
Lunch
[Closed Session for accepted ASI registrants only]
14:00 — 15:30
Workshop 6: Decoding large neural networks with advanced light sheet microscopy
[Closed Session for accepted ASI registrants only]
Session chairs: Zhiqin Chu and Mu He
Imaging large neural networks using tissue clearing, tissue expansion and tiling light sheet microscopy techniques
Liang Gao (with the assistance from Jiongfang Xie)
15:30 — 15:45
Tea break
[Closed Session for accepted ASI registrants only]
15:45 — 17:00
Discussion session on hot topics
[Closed Session for accepted ASI registrants only]
Session chair: Tom Cheung
Engineering and harnessing safe and immune-invisible cells to deliver therapeutic biologics
Andras Nagy
17:00 — 17:15
Closing remarks
Kathryn Cheah, Course Director, Advanced Study Institutes
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