Steven Holland, MD, is the Director of the Division of Intramural Research (DIR) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) in the US. Before he took on his current role, Holland served at NIAID as Chief of the Laboratory of Clinical Infectious Diseases (LCID). Holland continues to lead a programme at NIAID as chief of its immunopathogenesis section in the Laboratory of Clinical Immunology and Microbiology.

Holland’s research areas of special interest have included genetic conditions predisposing people to mycobacterial infections as well as chronic granulomatous disease, Job's syndrome (autosomal dominant STAT3 deficiency), and leukocyte adhesion deficiency. More recently, he has been interested in genetic conditions associated with severe coccidioidomycosis and acquired forms of anticytokine autoimmunity predisposing to opportunistic infections.

Holland is an NIH Distinguished Investigator and a member of the National Academy of Medicine.