Ryan Tse is a PhD student supervised by Helen Yan and SY Leung, investigating the tumour immune microenvironment in colorectal carcinoma. His research explores how genetic alterations influence dynamic tumour-immune cell interactions and crosstalk between immune components, alongside developing and refining tumour organoid co-culture models to uncover mechanisms of immune evasion. Furthermore, he is keen to explore emerging immunotherapies, including TCR-T and CAR-T cell therapies.