Chung Sze Or obtained her MPhil degree in 2021 from the Department of Pathology at University of Hong Kong. Her project aimed to study the molecular alterations crucial for acquiring anchorage independence in gastric cancer. Fifty-four patient-derived tumour organoids were evaluated in terms of cell-cell and cell-matrix anchorage dependence. Interestingly, only half of them were anchorage-independent, particularly those with RhoA activation or loss of the adhesion molecule E-cadherin. Throughout the study, she noticed heterogeneity between organoids obtained from the tumour surface and deeper tissue, prompting her to explore how the surrounding microenvironment affects cancer cell development. Recognising the critical role of the immune system in tumour progression, she decided to expand her expertise in immunology. She is currently pursuing a PhD in autoimmunity under the guidance of Vera Chan and CS Lau.