Professor Wong's immunology research includes (1) the elucidation of cytokine and chemokine network and intracellular signal transductions of immune effector cells including eosinophils, lymphocytes, mast cells, basophils, dendritic cells, in inflammatory diseases, with recent emphasizing in pattern recognition receptors mediated innate immunity and damaging inflammation, (2) the immunopathological mechanisms of allergic diseases, autoimmune diseases, infectious diseases and diabetes mellitus, with interdepartmental collaboration and (3) the immunomodulatory, anti-tumor and anti-allergic activities of traditional Chinese medicine.