The project aims to increase understanding of autophagy regulation in general, provide novel biomarkers for autophagy-related human disease diagnosis, and promote the application of autophagy-based approaches in the treatment and prevention of human...
The Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis aims to develop new SIOCPhox ligands and new tetrahydroxytetraphenylene catalysts for the novel C-C bond formation reactions, and to strengthen research collaboration between Hong Kong and...
Developing an effective and rapid technology to detect and grade a melanoma early is critical to the survival of all skin cancer patients worldwide. Scientists at the City University of Hong Kong and the Shenyang Institute of Automation explore the...
Integrated circuit feature size is shrinking rapidly and the smallest features of all are the vias that connect layers. Performance and yield depend on achieving a reliable connection through the via and this project investigated the feasibility of...
Osteosarcoma is a common and deadly cancer among
children around the world. This project aims to study and develop a triptolide-aptamer
conjugate as a potential anti-cancer agent for osteosarcoma.
The Shanghai Hong Kong Joint Laboratory in Chemical Synthesis (Joint Lab) was established in 1999 as a tripartite arrangement between Shanghai Institute of Organic Chemistry, the Chinese University of Hong Kong, and the University of Hong Kong.
Professor Shuit-tong Lee, Chair Professor of Physics and Materials Science at the City University of Hong Kong and Professor Xiaohong Zhang of the Chinese Academy of Sciences Technical Institute of Physics and Chemistry in Beijing have made significant...
This project aims to develop new reactions based on selectivity of the reaction of π-allyl transition metal complexes with nucleophiles, novel asymmetric reactions based on superbase organocatalysis for the novel C-C bond formation reactions, and...
Cubic boron nitride is structurally similar to diamond: both have strong covalent bonds and high atom density that give them extreme physical and chemical properties. This project is focused on the controlled growth of diamond and cubic boron nitride...
Buildings like Dubai's Burj Khalifa and the International Commerce Centre in Hong Kong are among the greatest feats of human engineering. But designing effective fire safety systems for these structures is a challenge. Researchers in Hong Kong and...
This project aims to develop new synthetic
methodologies for making functionalised carboranes using metallacycles designed
for specific reactivity, and explore their potential applications in medicine
and materials synthesis.
Encoding and retrieval of artificial visuo-auditory memory traces in the auditory cortex of the brain needs the entorhinal cortex, and a special chemical.
Bacteria in sea sponges and soft corals produce compounds with pharmaceutical and antifouling properties, studies find.
The Internet is evolving into a heterogeneous network of networks, with different component networks which may be wired and wireless and may have widely varying network characteristics. In this project a testbed was constructed to study peer-to-peer...
Phosphorescent transition metal complexes have been shown to play pivotal roles in diverse areas such as solar to chemical energy conversion, optoelectronic devices, and theranostic agents.
This joint laboratory will discover potentially pathways for modulation of LDL levels in blood and the management of hyperlipidemia.
Developing genetic engineered iPSC and ESC lines to gain further insight into the regulatory mechanism and better tracking of specific lineages, gene editing and tagging.
This project aimed to link the rich resources of Chinese herbal medicines from China with the advanced equipment and technologies in Hong Kong to achieve a complete scientific validation of the efficacy of traditional Chinese medicine.
In the contest of developing solar energy as a renewable energy source, there is a global interest to develop highly robust metal catalysts/photochemical active semi-conductor materials for efficient water oxidation and carbon dioxide reduction under...
With an increasing demand
for energy coupled with dwindling resources worldwide, scientists are looking
for innovative ways of sourcing alternative energy.
Serious bone fractures require prompt surgery to
fix bone fragments and to prevent degeneration and further impairment and
complications. However, a second round of surgery is required to remove the permanent
implants after fractures heal. This...
This is a large-scale investigation into the ethylene-regulated metabolism of Arabidopsis, a small cabbage-like plant. It will eventually be applied to the genetic engineering of agricultural crops for more efficient food and bioenergy production.
The development of effective catalysts for clean processes with energy or reagent economy is of fundamental importance both in basic research and industrial applications.
This study brings together two internationally recognised experts on plant cell biology and rice genetics to work on the molecular mechanisms of yield and abiotic stress tolerance in rice, with the long-term goal of establishing a joint laboratory and...
Nano-science and technology is an internationally important scientific field with huge potential development and significance in the future. Nano-twinned metals an area of high research interest.
Neutron scattering is a powerful and versatile method to characterise the structure and dynamics of materials. The experimental technique was pioneered in the late 1940s, by Drs. Clifford 0.Shull and Bertram N. Brockhouse, for which they were awarded...
This joint laboratory will continue the previous Joint CAS-Croucher Laboratory on Neutron Scattering Science and Technology, which is designed to provide a platform for collaboration on neutron scattering between the Hong Kong scientific community and...
Predicting the weather? Controlling animal patterns? Uncovering deep secrets of universe? All these can be managed by a set of equations, called Partial Differential Equations. The interdisciplinary study of these PDEs and Nonlinear Analysis provides a...
Recent advances in photovoltaic technology have
lowered its cost, made it more environmentally friendly, and lowered the energy
consumption during production. Organic solar cells have great potential as a
cheap renewable energy source for the future....
The overall goal of the project is to understand how fat storage organelle heterogeneity is enforced by a novel sub-cellular structure, termed peri-lipid droplet (LD) cage. The team will comprehensively identify the functional roles of peri-LD cage...