Optical bio-manipulation
Investigating bio-manipulation and bio-marking through optically-induced electrokinetics.
Optically-induced dielectrophoresis (ODEP) offers a cost-effective alternative to laser-based tweezers, enabling parallel manipulation of hundreds of micron-scale cells and high-throughput separation of nano-scale particles. Research teams have developed ODEP platforms demonstrating large-scale micro/nano-scale manipulation and discovered that pigmented cells can undergo self-induced rotational motion in a dielectrophoretic force field, which could serve as a bio-marker for separating pigmented and non-pigmented cells. The project aimed to use automation and digitally generated DEP forces for dynamic cell manipulation and to explore the potential of DEP-induced rotation as a bio-marking mechanism.
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Original project funded for three years from 2012
Key topics
- Optically-induced electrokinetics
- Cancer cell detection
- Bio-manipulation techniques
- Dielectrophoretic rotation
- Automated medical technologies
Directors
Wen Jung Li
Chair Professor of Biomedical Engineering at the City University of Hong Kong
Yuechao Wang
Professor at Shenyang Institute of Automation, Chninese Academy of Sciences
Other projects
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Original project funded for three years from 2024
Chiral electronic materials
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Treg heart regeneration
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