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Fan Bai is deputy director and professor at the Peking University Biomedical Innovation Center, Investigator at the Beijing Advanced Innovation Center for Future Genomic Diagnostics, and Joint Investigator at the Peking-Tsinghua Center for Life Sciences. He is a recipient of both the National Science Fund for Excellent Young Scholars and the National Science Fund for Distinguished Young Scholars. After earning a bachelor's degree in Physics from Peking University in 2003 and a PhD in biophysics from the University of Oxford in 2008, Bai returned to China in 2011 to establish his independent research lab. His team has since focused on the innovation and application of single-cell technologies across interdisciplinary biomedical fields. He was the first to report whole-genome sequencing of single circulating tumour cells (CTCs), advancing non-invasive cancer diagnostics. His lab also developed laser microdissection and low-input sequencing techniques, revealing heterogeneity in liver cancer metastases and identifying clonal expansions in morphologically normal urothelium. Through single-cell transcriptomics and immune profiling, he discovered unique epithelial-immune traits in nasopharyngeal carcinoma and elucidated key mechanisms in peadiatric inflammatory bowel disease and biliary atresia. Additionally, his group has investigated bacterial antibiotic resistance using single-cell fluorescence imaging and sequencing, offering deep insights into microbial drug resistance mechanisms.
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