Registration and welcome coffee

Welcome and opening remarks

• 9:00 - 9:05: Welcome and introduction by Professor Gao Zhang (Faculty of Dentistry, University of Hong Kong)
• 9:05 - 9:10: Remark by Dean and Professor Lijian Jin (Faculty of Dentistry, University of Hong Kong)

Session 1: Single-cell Insights into cancer heterogeneity

• Session chair: Professor Yulan Deng (Department of Thoracic Surgery and Institute of Thoracic Oncology, Sichuan University)
• Talk:
  • Speaker: Fan Bai, PhD (Peking University Biomedical Innovation Center; Beijing Advanced Innovation Center for Future Genomic Diagnostics; Peking-Tsinghua Center for Life Sciences)
  • Title: Whole genome analysis of Chinese cancers

Coffee break and networking; group photo

Session 2: Innovations in melanoma therapies and biomarkers

• Session chair: Professor Martin Cheung (University of Hong Kong) 
• Talk:
  • Speaker: George Xu, M.D., PhD (Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania)
  • Title: Beyond checkpoints: engineered CAR T-Cell and extracellular vesicle therapies for melanoma

Coffee break and networking

Lunch and break

Southside Bistro (L4, Le Méridien Hong Kong)

Session 3: Artificial intelligence in skin oncology

• Session chair: Professor Richard Su (University of Hong Kong) 
• Talk:
  • Speaker: Titus J. Brinker, PhD (German Cancer Research Centre (DKFZ); University of Heidelberg)
  • Title: Artificial intelligence-driven diagnosis of skin cancer

Coffee break and networking

Session 4: Panel discussion – Computational biology meets cancer biology

• Moderators: Professor John Wang and Professor Shi Huang (University of Hong Kong)
• Panelists:
  • Fan Bai, PhD (Peking University)
  • Yuanhua Huang, PhD (University of Hong Kong)
  • Yulan Deng, PhD (Department of Thoracic Surgery and Institute of Thoracic Oncology, Sichuan University) 
  • Zhenyu Yang, MD (Department of Thoracic Surgery and Institute of Thoracic Oncology, Sichuan University)

Break

Welcoming dinner

Participants: Nam Fong Dining Hall ( L3, Le Méridien Hong Kong)

Speakers and organising committee members: One Harbour Road, Grand Hyatt Hong Kong, 7-8/F (Address: 1 Harbour Road, Wan Chai; Exit B3, Exhibition Centre MTR Station)

Session 5: Precision advances in thoracic surgery

• Session chair: Professor David Lam (University of Hong Kong)
• Talk:
  • Speaker: Lunxu Liu, M.D. (West China Hospital, Sichuan University)
  • Title: Precision lung cancer surgery

Coffee break & networking

Session 6: Mapping cellular societies with multimodal data

• Session chair: Professor Wei Zhang, M.D. (School of Stomatology, Wuhan University)
• Talk:
  • Speaker: Yuanhua Huang, PhD (University of Hong Kong)
  • Title: Fusing spatial transcriptomics and histological images for high-resolution cellular interaction and somatic clones

Coffee break and networking

Lunch and break

Nam Fong Dining Hall (L3, Le Méridien Hong Kong) Chinese Lunch -Menu A

Session 7: Myeloid cells in immune suppression

• Session chair: Professor Zhenyu Yang, M.D. (Department of Thoracic Surgery and Institute of Thoracic Oncology, Sichuan University) 
• Talk:
  • Speaker: Dmitry Gabrilovich, M.D., PhD (AstraZeneca, USA)
  • Title: Immune suppressive myeloid cells: from biology to therapeutic targeting

Session 8: Panel discussion - Precision therapies and clinical trials in advanced cancers

• Moderator: Professor David Lam (University of Hong Kong)
• Panelists
  • Lunxu Liu, M.D. (Sichuan University)
  • Shiyou Wei (Sichuan University)
  • Dainan Zhang, M.D. (Capital Medical University)
  • Wei Zhang, M.D. (Wuhan University)

Session 9: Overcoming challenges in CNS tumors

• Session chair: Professor Gilberto Leung (University of Hong Kong) 
• Talk:
  • Speaker: Yudan Chi, PhD (Institute for Translational Brain Research and Research Institute of Huashan Hospital, Fudan University)
  • Title: Profiling and decoding the brain border immunosuppressive microenvironment in leptomeningeal metastasis

Break

Dinner for invited speakers

Umami (L1, Le Méridien Hong Kong)

Welcome coffee and networking

Session 10: Targeting cancer signaling pathways I

• Session chair: Professor Ui Soon Khoo (University of Hong Kong)
• Talk:
  • Speaker: Patrick Casey, PhD (Cancer and Stem Cell Biology Programme, Duke-NUS Medical School)
  • Title: Involvement of GNA12/13 signaling in cancer cell invasion and survival

Coffee break & networking

Session 11: The yin-yang of cancer genomes

• Session chair: Professor Duo Zhang (Faculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology)
• Talk:
  • Speaker: Professor Jason Wong, PhD (School of Biomedical Sciences, University of Hong Kong)
  • Title: Discovery and applications of intrinsic and extrinsic mutational processes from cancer genomes

Lunch and break

Nam Fong Dining Hall (L3, Le Méridien Hong Kong) Chinese Lunch - Menu B

Session 12: Targeting cancer signaling pathways II

• Session chair: Professor Shi Huang (University of Hong Kong) 
• Talk:
  • Speaker: Mei Wang, PhD (Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore; Duke-NUS Graduate Medical School)
  • Title: The path of targeting ICMT in cancer therapy

Session 13: Flash talks

• Speaker 1: Yulan Deng, PhD (Department of Thoracic Surgery and Institute of Thoracic Oncology, Sichuan University)
  • Title: Multicellular ecotypes shape progression of lung adenocarcinoma from ground-glass opacity towards advanced stages
• Speaker 2: Duo Zhang, PhD (Faculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology)
  • Title: Reprogramming the glioblastoma microenvironment to overcome barriers to CAR-T therapy
• Speaker 3: Wei Zhang, M.D. (School of Stomatology, Wuhan University)
  • Title: Elucidating the molecular mechanisms of immunotherapy resistance in oral squamous cell carcinoma based on spatial transcriptomics

Meeting recap and future directions