Ka Chi Chu (朱家摯)
University of Hong Kong
Ka Chi Chu graduated in 2024 and is currently working as a postdoctoral researcher under the supervision of Professor Kathryn Cheah. Ka Chi's research interests center on developmental biology and stem cell models, focusing on early human embryonic developmental processes such as gastrulation and axis formation. During Ka Chi's PhD studies, research investigated the mechanisms of inner ear defects caused by a clinically common campomelic dysplasia SOX9 mutation using mouse models, organoids, and bioinformatics—revealing a conserved SOX9–Wnt–SOX10 regulatory network in embryonic otic development. Currently, Ka Chi's research focuses on understanding the development of the axial mesoderm lineage (from the node to the notochord and nucleus pulposus) using single-cell transcriptomic profiling, alongside establishing differentiation protocols with human pluripotent stem cells (hPSCs) to recapitulate this trajectory for genetic and molecular study.