Chao Xie (解超)
Centre for translational stem cell biology
My previous research mainly focused on cytoskeleton regulation and neural development in C. elegans. Recently, I joined Prof. Pengtao Liu's lab as a postdoctor to conduct tumorigenesis and cancer immunotherapy related projects. In our lab, we have the human expanded potential stem cells (hEPSCs) which possess the expanded potency for both embryonic and extraemryonic cell lineages. Now we are trying to develop the protocol to generate NK cells and T cells from our hEPSCs for cell-based cancer immunotherapy. We are investigated in the function of p53 protein in hEPSCs differeation and proliferation. We expect to explore how p53 functions in normal development, and how these functions are relevant to its tumor suppression functions.