Blue Lui is a PhD student in cell and molecular biology with a focus on neurodevelopmental biology. Her research concentrates on the transcription factor Yin Yang 1 (YY1), where mutations give rise to YY1 haploinsufficiency syndrome and associated neurological impairments in central nervous system development. Utilizing transgenic mouse models and cerebellar organotypic cultures, Blue investigates the transcriptional niches through which YY1 regulates the development of Purkinje cells—a distinct class of cerebellar neurons. Because Purkinje cells account for only about 5% of all cerebellar neurons, she plans to incorporate single-cell studies and live-cell imaging to analyze the intracellular activity within mutant Purkinje cells and advance her ongoing research.