I am currently a post doctoral fellow and I am studying the role of Tubulin Alpha4A in neurons to unravel its implication in ageing and in neurodegenerative diseases. For this project, I am working with induced motor neurons differentiated from iEPSCs and our own model of induced Neural Stem Cells. Using super resolution microscopy and different functional assays, I am studying the integration of this isoform within the microtubules and I am trying to understand its function in Amyotrophic Lateral sclerosis patients cells. I am currently working on 2D cultures but I am interested in organoids system which could improve the maturity of the neurons and allowed the cocultures with glial cells which might have a role in the disease development.