Prof Grant J JENSEN
Professor of Biophysics and Biology, California Institute of Technology
Professor of Biophysics and Biology
Investigator, Howard Hughes Medical Institute (HHMI)
California Institute of Technology (Caltech)
Expertise: Cellular electron cryo-tomography and method development
Grant J. Jensen graduated from Brigham Young University in 1994 and received his PhD from Stanford University in 1999. He joined Caltech since 2002 and become HHMI Investigator since 2008.
The Jensen Lab uses Electron Cryotomography (ECT) to study the molecular architecture of microbial cells and HIV in their native state. They focus on fundamentals of microbial cell biology such as cell division, movement and secretion, as well as the structure of HIV at all stages of its lifecycle.
List of Key Publications :
1. Chang Yi-Wei, Kjær A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK and Jensen GJ* (2017). Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography. Nature microbiology, 2, 16269.
2. Chang Y W, Rettberg L A, Treuner-Lange A, Iwasa J, Søgaard-Andersen L and Jensen GJ* (2016). Architecture of the type IVa pilus machine. Science, 351(6278), aad2001.
3. Nguyen LT, Gumbart JC, Beeby M and Jensen GJ* (2015). Coarse-grained simulations of bacterial cell wall growth reveal that local coordination alone can be sufficient to maintain rod shape. Proceedings of the National Academy of Sciences, 112(28), E3689-E3698.
4. Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L and Jensen GJ* (2014). Correlated cryogenic photoactivated localization microscopy and cryo-electron tomography. Nature methods, 11(7), 737-739.
5. Shikuma NJ, Pilhofer M, Weiss GL, Hadfield MG, Jensen GJ and Newman DK (2014) Marine tubeworm metamorphosis induced by arrays of bacterial phage tail–like structures. Science, 343(6170), 529-533.