Dr Martin BECK
GROUP LEADER AND SENIOR SCIENTIST, European Molecular Biology Laboratory (EMBL)
European research council (ERC) Investigator
Group Leader and Senior Scientist
European Molecular Biology Laboratory (EMBL) Heidelberg
European Research Council (ERC) Investigator
Expertise: Integrative structure determination of macromolecular assemblies
Martin Beck graduated from the Martin-Luther-University Halle-Wittenberg with a diplomat in Biochemistry in 2001. He started his PhD study at Max Planck Institute of Biochemistry, Martinsried, Germany under the supervision of Prof. Wolfgang Baumeister in 2002. He was awarded PhD in life sciences, ‘summa cum laude’ by The Technical University of Munich in 2006. He worked as postdoctoral fellow at the Institute for Molecular Systems Biology from 2006-2009. Then, he joined the European Molecular Biology Laboratory (EMBL) and is the Group leader at the Structural and Computational Biology Unit.
Research in the Beck group combines biochemical approaches, proteomics and cryo-electron microscopy to study large macromolecular assemblies.
List of Key Publications :
1. Teimer R, Kosinski J, von Appen A, Beck M and Hurt E (2017). A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex. Nature communications, 8(1), 1107.
2. Beck M and Hurt E (2017). The nuclear pore complex: understanding its function through structural insight. Nature Reviews Molecular Cell Biology, 18(2), 73-89.
3. Hampoelz B, Mackmull MT, Machado, P, Ronchi P, Bui KH, Schieber N, Santarella-Mellwig R, Necakov A, Andrés-Pons A, Philippe J. M, Lecuit T, Schwab Y, Beck M and Lecuit T (2016). Pre-assembled nuclear pores insert into the nuclear envelope during early development. Cell 166(3), 664-678.
4. Ferber M, Kosinski, J, Ori A, Rashid UJ, Moreno-Morcillo M, Bouvier G, Batista PR, Müller CW, Beck M and Nilges M (2016). Automated structure modeling of large protein assemblies using crosslinks as distance restraints. Nature methods, 13(6), 515-520.
5. Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuilio AL, Wan W, Bui KH, Hagen WJH, Briggs JAG, Glavy JS, Hurt E and Beck M* (2016). Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science, 352(6283), 363-365.