Quan Wen is a neuroscientist dedicated to understanding how collective neural circuit activities give rise to complex behaviours. His research focuses on precisely describing behaviours, identifying the neural computations driving them, and uncovering the biophysical mechanisms by which neurons and synapses implement these computations. Currently, he uses C. elegans as a model system to study the neural basis of sensorimotor behaviours. With its simple nervous system of 302 neurons, a fully mapped connectome, and exceptional genetic tractability, C. elegans offers a unique platform for exploring sensorimotor transformations at both algorithmic and mechanistic levels.